Does Amphotericin B interact with other medications?

Always consult your healthcare professional (e.g., doctor or pharmacist) before taking amphotericin B. Till date, a total of 155 drugs have been reported to be interacting with amphotericin b.

• 38 major drug interactions (interaction might cause very harmful effects) with:
  1. Foscarnet (nephrotoxic)
  2. Inotersen (nephrotoxic)
  3. Pentamidine (nephrotoxic)
  4. Tubocurarine (increased muscle relaxant effect)
  5. Clozapine (myelosuppressive)
  6. Deferiprone (myelosuppressive)
  7. Cyclosporin (nephrotoxic and neurotoxicity)
  8. Digitalis glycosides

• 110 moderate drug interactions (interactions might cause some risk when taken together) with:
  1. Corticosteroids; corticotropin (ACTH) (hypokalaemia)
  2. Adefovir (nephrotoxic)
  3. Immune globulin IV (IGIV) (nephrotoxic)
  4. Tenofovir (nephrotoxic)
  5. Gentamicin
  6. Stimulant laxatives (hypokalaemia)

• 7 minor drug interactions

See also:

• What is amphotericin B?
• List of side effects of Amphotericin B
• Who should not take Amphotericin B?
• Is Amphotericin B safe during pregnancy?

Related Blogs:

• Story of The Black and White Devils – Mucormycosis

References:

• Hamill, R. J. (2013). Amphotericin B Formulations: A Comparative Review of Efficacy and Toxicity. Drugs, 73(9), 919–934. doi: 10.1007/s40265-013-0069-4
• Drugs.com